Sperm Preservation with Zero Source of Disease Transmission.
Sperm Preservation with Zero Source of Disease Transmission is a demand of time. Which is going to be a necessity in future. Rather waiting for some disaster it will be insightful to make mandatory provision for Sperm Preservation with Zero Source of Disease Transmission.
The most ideal approach to accomplish this objective will be to utilize 100% chemically defined sperm freezing media. Which don’t contain any human, animal, avian or any crude protein of any origin. The best way to achieve this target will be to use 100% chemically defined sperm freezing media. Which do not contain any human, animal, avian or any crude protein of any origin.
Sperm Freezing – Present Status
By and by all sperm freezing media manufacturer of world are utilizing either Human serum albumin, Egg white, Fetal bovine serum or Egg yolk as a maintenance meal of vitality or to enhance cryopreservation of human sperm.
Sperm freezing media manufacturer are ensuring that used serum or protein is suitably treated by different advance methodology. And source materials used are seen to be non-reactive to antibodies for Hepatitis B and C, Human immunodeficiency virus (HIV), etc. At the same time they (Sperm freezing media manufacturers) are also warning that all human source material should be treated as if it were capable of transmitting infection as the possibility of transmitting infective agents, including unknown or emerging viruses, cannot be totally excluded.
It is likewise being declared by all Sperm freezing media manufacturer – no test method offers total confirmation that items got from human sources are noninfectious. It remain in their statement — Handle all human source material as though it were suitable for transmitting disease. In the medical safety data sheet (MSDS) of all manufacturer states that they will not be held responsible for any harm coming about because of use of or from contact with the item since it contain Human serum albumin.
There are reports that whole batch of Human serum albumin had been taken back from the market in the wake of perceiving some infective materials. Be that as it may, no figure is accessible showing number of people got contamination because of infected human serum albumin.
Creutzfeldt-Jakob Disease (CJD) is showing its clinical symptom and positive test report even twenty years after infection. It is hard to analyze or identify even the carrier stage of this disease in cattle . There are reports, CJD had been diagnosed decades after using human / animal protein. And patient could not be diagnosed earlier.
Bird Flue / Avian Influenza/ Zika Virus
Bird flue / avian influenza is spreading all over world. Now it’s a known cause of morbidity & mortality. As of late analyzed infection like Zika Virus is an ongoing risk. Which yet should be forestalled.
Un-identified and Emerging viruses the biggest threat which will always remain a challenge for medical science.
Endotoxins & Bioactive Particle
Human serum albumin or any animal protein is susceptible to contain different amounts and type of endotoxins. Other unfavorable components and possible bioactive particles is making additional threat. Serum can be a potential source of microbial contaminants, for example fungi, microscopic organisms, infection or prions.
Ethical & Religious issue
There might be some moral & ethical issue or religious motivation to not use Human or Animal protein. There is a fair chance to get infected during transportation as human or animal protein is an excellent nutritional source to micro-organism. During transportation chance of getting infected is much higher, as cold chain may not be maintained in adverse condition.
With the above idea we have built up a new innovative Sperm freezing media. The new sperm freezing medium / sperm cryo-preservative medium which does not have any human, animal , bird or any unrefined protein. It is 100% synthetically characterized. It contain amino acids, Sodium hyaluronate, glycerol, sucrose and so forth. In the term of post thaw recovery of sperm it is in the same class as by and by conventional cryo-preservative media. We are first on the planet , going to safeguard human sperm with zero additional source of disease transmission. . It is a measure to avoid transmission of disease through the sperm when fruitlessness especially male infertility is expanding all over world.
This cryo-preservative media might be additionally a model for cryopreservation of other tissue and organs.
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